Goal

Using illustrative examples, lectures will explain the basics of inter- and
intracellular communication, the different techniques to study cell responses and the
complementarity between experimental approaches at different scales.

Content

Signal transduction at the plasma membrane
Second messenger production
Regulation of protein activity by phosphorylation
Signal transduction to the nucleus and transcription regulation
Termination of cell responses
G-protein coupled receptors
Receptors with tyrosine kinase activity
Control of the eukaryotic cell cycle
Molecular basis of cancers

Prerequisites

Molecular and cellular biology

Bibliography

Stryer : Biochemistry, filth edt, Freeman
http://bcs.whfreeman.com/biochem5/
Alberts et al. Molecular biology of the cell fouth edt. Garland
http://www.ncbi.nlm.nih.gov/books